Destroy All Humans! 2 is an action-adventure video game developed by Pandemic Studios. It is the sequel to Destroy All Humans! and launched on August 30, 2022, for Microsoft Windows, PlayStation 5, and Xbox Series. The game is set in the same time period and city–1960s in a fictional San Francisco called Bay City–along with other locations inspired by places like London, the Soviet Union, and Tokyo. You will even travel to the Moon to revenge for the destruction of the mothership.