Antidote
0:05 Reach Ashbury’s Mansion
2:46 Talk to Lady Ashbury
6:02 Reach Pembroke Hospital’s Morgue
9:59 Search for insulin in the old morgue of the Pembroke hospital.
12:18 Reach Stonebridge Cemetery
14:20 Obtain a drop of King Arthur’s blood from Geoffrey McCullum
17:44 Reach Ascalon Club in West End
21:10 Obtain a drop of William Marshall’s blood from Lord Redgrave
Head back outside the theatre and make your way to Lady Ashbury’s house. After talking to her, you will be in the final stretch of the game and should complete any side quests or anything else that you want to do, since after you fight the final boss, you will be locked into the epilogue forever and will be unable to come back to the main area of the game.
With that being said, you are tasked with gathering 3 items to use in the final battle, go and obtain them in whatever order you wish. When attempting to gather the blood from lord Redgrave, if you chose to kill Aloysius Dawson, then you must sneak around the back of the house in order to get in to talk to him.
Once you gather all 3 ingredients, head to any hideout to craft the serum and then head back to the Skal hive to have your final boss fight.
Guinea Pig
0:14 Reach the hive
2:12 Locate Harriet Jones (follow the blood trail)
6:51 Kill Disaster Harriet (Boss Fight)
9:20 Defeat Red Queen’s Avatar (Boss Fight)
This boss has 2 forms, the first is almost exactly like Doris Fletcher, so act accordingly. The second form however, can be a very long fight that must be played very carefully depending on your level, because you definitely don’t want to die and have to do it all again. The boss’s level will scale with yours, and oddly
enough, is actually way easier at lower levels due to your weapons being independent of your level and likely being a lot stronger than you are at lower levels. So for this final part of the game, NOT killing the NPCs is actually the easier difficulty.
Once you have finished the boss off, Old Bridget will appear and congratulate you and give you some final plot information. And with that, congratulations, you have beaten Vampyr!
Healthy Carrier (Epilogue)
4:21 Find a away to enter the castle
5:14 Explore the castle
5:30 Locate the secret passage
6:44 Confront Lady Ashbury
The final chapter of the game serves as an epilogue and has no combat, and no alternate paths or anything of that nature. Instead, simply make your way into the castle via the cracked wall to your left.
After getting inside, make your way to the main room (the one with the huge painting) and use your Vampire senses on it. This will reveal a sword and a moon, which are the panels that you need to press in order to find the secret path leading to the basement, and Lady Ashbury.
From here, simply talk to the characters that are downstairs to learn as much as you want about the story. After that, the final cutscenes will roll, and depending on your decisions throughout the game, you will witness one of four possible endings, followed by the credits!